| Popis: |
Mechanical ventilation is a life-saving intervention for neonates with respiratory failures. Through intubation, mechanical ventilators help patients achieving normal oxygen and carbon dioxide levels in the artery and minimizing heavy breaths. However, the use of mechanical ventilation, especially on prolonged case, in neonates can cause complications. The process of weaning off mechanical ventilation, therefore, needs to be carefully carried out to minimize re-intubation. One of the clinical parameters measured prior to extubation is oxygenation index (OI), which is the measurement of oxygen exchange in the lungs representing lung dysfunction. Objective : to analisis the relationship between oxygenation index and extubation outcome in neonatus using mechanical ventilation. Material and Methods: This research was an observational cross-sectional research to assess the relationship between the success of extubation and OI in neonates using mechanical ventilation in Haji Adam Malik hospital, Medan, Indonesia between February and May 2022. Results: OI 4.5% was categorized as high. There were 50 neonates involved in this research, where 5 (10%) neonates were below 28 weeks’ gestational age and 7/50 (14%) neonates had extubation failure. The mean OI was 1.62%, where 47 (94%) neonates had low OI and 3 (6%) neonates had high OI. The relationship OI and the success of extubation on neonates was analyzed using Fischer’s exact test. All three neonates with high index had extubation failure. On the other hand, only 4 (8.5%) out of 47 neonates with low OI had extubation failure. The analysis by Fischer’s exact test showed a significant relationship between OI and the success of extubation in neonates using mechanical ventilation (p=0.002). Conclusion: Low oxygenation index can be used as succesfull of extubation in neonatus |
