Is trisomy 18 increasing in Sweden? An analysis of the syndrome during a ten year period and a comparison with a French registry
| Autor: | Pierre Pradat, Elisabeth Robert |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Down syndrome Pediatrics Aneuploidy Trisomy Biology Sex Factors Pregnancy Prenatal Diagnosis Epidemiology Prevalence Genetics medicine Humans Abnormalities Multiple Registries Sweden Infant Newborn Infant General Medicine medicine.disease Child Preschool Female France Chromosomes Human Pair 18 Maternal Age |
| Zdroj: | Hereditas. 114:97-102 |
| ISSN: | 0018-0661 |
| DOI: | 10.1111/j.1601-5223.1991.tb00558.x |
| Popis: | This paper reports an analysis of trisomy 18 in Sweden between 1978 and 1987 and a comparison with data from the Rhône-Alpes/Auvergne registry in France. A strong maternal age dependency is seen, which parallels that observed for Down syndrome. The patterns of registered malformations in the two data sets are quite similar. A progressive increase of the prevalence at birth of trisomy 18 is seen in Sweden during the ten years but not in France. This increase seems to result, at least in part, from an increased identification of the trisomy among malformed infants. A parallel decrease in the reporting of infants with the "cardinal" trisomy 18 malformations is indicated. |
| Databáze: | OpenAIRE |
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