Rubella-specific IgM in reinfection and risk to the fetus
Autor: | Mali Zolti, Zion Ben-Rafael, Alice Fogel, David Bider, Shlomo Mashiach |
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Rok vydání: | 1990 |
Předmět: |
Adult
Rubella Syndrome Congenital medicine.disease_cause Rubella Rubella vaccine Antibody Specificity Pregnancy Risk Factors Medicine Humans Rubella Vaccine Pregnancy Complications Infectious Abortion Therapeutic Hemagglutination assay biology business.industry virus diseases Obstetrics and Gynecology Rubella virus medicine.disease Virology Titer Reproductive Medicine Immunization Immunoglobulin M Immunology biology.protein Female business medicine.drug |
Zdroj: | Gynecologic and obstetric investigation. 30(3) |
ISSN: | 0378-7346 |
Popis: | A case of reinfection with the wild rubella virus in the 8th gestational week is reported. The patient had preexisting hemagglutination inhibition antibodies of low titer following immunization with rubella vaccine. Reinfection was accompanied by clinical symptoms and the presence of rubella-specific immunoglobulin M (IgM) of high titer. Following termination of pregnancy no rubella virus could be isolated from the fetal tissues and the fetal blood contained no specific IgM antibodies. These results should encourage the use of cordocentesis before decision on interruption of pregnancy. |
Databáze: | OpenAIRE |
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