Low-Density Lipoprotein Apheresis for Focal Glomerular Sclerosis
| Autor: | Michio Yamakido, Sayuri Okushin, Dai Amimoto, Yoji Nishida, Yoshihiko Taniguchi, Noriaki Yorioka |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Serum albumin Steroid Internal medicine Hyperlipidemia medicine Humans biology Glomerulosclerosis Focal Segmental business.industry Glomerulosclerosis Plasmapheresis General Medicine medicine.disease Lipoproteins LDL Endocrinology Apheresis LDL apheresis Creatinine biology.protein Female lipids (amino acids peptides and proteins) business Lipoprotein |
| Zdroj: | Therapeutic Apheresis. 1:370-371 |
| ISSN: | 1091-6660 |
| DOI: | 10.1111/j.1744-9987.1997.tb00058.x |
| Popis: | We report on a 22-year-old female with focal glomerular sclerosis and hyperlipidemia who did not respond to long-term steroid or immunosuppressant therapy. When low-density lipoprotein (LDL) apheresis was performed, her total daily protein excretion decreased, serum albumin increased, total cholesterol decreased from 1,052 mg/dl to 148 mg/dl after 3 months, and the serum lipoprotein(a) level also decreased from 117.8 mg/dl to 9.1 mg/dl. After this therapy, her clinical course was well maintained. By controlling hyperlipidemia, including oxidized low-density lipoprotein and lipoprotein(a), low-density lipoprotein apheresis may produce clinical improvement in focal glomerular sclerosis. |
| Databáze: | OpenAIRE |
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