Differential metabolomic profiles of two closely related Leuciscinae fish, the species Ctenopharyngodon idellus and Leuciscus idus
| Autor: | Jianguo Yin, Jun Wang, Xiaowen Chen, Chenghui Wang, Jingan Wang, Hua Han, Maocheng Yang, Xin Hou |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Taurine
SH1-691 Hypotaurine Aquaculture Aquatic Science Serine Superoxide dismutase 03 medical and health sciences chemistry.chemical_compound Metabolomics Aquaculture. Fisheries. Angling 030304 developmental biology 0303 health sciences Leuciscinae biology 04 agricultural and veterinary sciences Metabolism biology.organism_classification Immune chemistry Biochemistry 040102 fisheries biology.protein 0401 agriculture forestry and fisheries Animal Science and Zoology Leuciscus idus |
| Zdroj: | Aquaculture Reports, Vol 20, Iss, Pp 100650-(2021) |
| ISSN: | 2352-5134 |
| Popis: | Ctenopharyngodon idellus and Leuciscus idus are two closely related Leuciscinae fish with dramatically different physiologies, especially in terms of immunological performance. However, the intrinsic metabolic difference between these two species has not been fully discovered. In this study, the immunological indexes, such as lysozyme, superoxide dismutase, and alkaline phosphatase activities, and plasma metabolomic profiles of the two species were compared. Our study revealed significant differences in immunological indexes and metabolomic profiles between them. In C. idellus, highly abundant metabolites were enriched in galactose metabolism, pyruvate metabolism, choline metabolism, and ether lipid metabolism. By contrary, in L. idus, highly abundant metabolites were enriched in taurine and hypotaurine metabolism, glycine, serine and threonine metabolism, and glycerophospholipid metabolism. We also identified that the abundances of key immune-performance-related metabolites, such as taurine, betaine, glutathione, gluten exorphin, and fistuloside A were higher in L. idus than in C. idellus. This result indicated that the two species presented distinct immunological performance at metabolomic level. Our study provided a snapshot of the metabolic difference between C. idellus and L. idus, and the key metabolites identified here could be utilized as immunological biomarkers for the aquaculture and selective breeding of C. idellus in the future. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|