Cyr61, a marker of progesterone activity in normal and hyperplasic endometrium of female dogs
| Autor: | Fabiana Azevedo Voorwald, Renée Laufer Amorim, Diogo José Cardilli, Caio de Faria Tiosso, Carolina F. João, Gilson Hélio Toniollo |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
business.industry
medicine.drug_class Angiogenesis media_common.quotation_subject Endometriosis General Medicine Endometrium medicine.disease General Biochemistry Genetics and Molecular Biology Endometrial hyperplasia Andrology medicine.anatomical_structure Estrogen CYR61 Follicular phase Poster Presentation Medicine business Menstrual cycle Biomedical engineering media_common |
| Zdroj: | BMC Proceedings |
| ISSN: | 1753-6561 |
| DOI: | 10.1186/1753-6561-7-s2-p22 |
| Popis: | Background Cysteine-rich protein 61 (CYR61/CCN1) is a growth factor-inducible gene, involved in the regulation of multiple cellular processes, such as cell adhesion, migration, survival, growth factor-induced mitogenesis, endothelial tubule formation, apoptosis and angiogenesis. In normal women endometrium, CYR61 expression is elevated during the proliferative phase of the menstrual cycle, and reduced during the midsecretory phase. However, CYR61 expression is deregulated in endometrium with estrogen dependent diseases, such as endometriosis, polycystic ovarian syndrome, endometrial hyperplasia and adenocarcinoma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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