Peripheral neuropathy and depressive symptoms: examining the association in a primary health care setting among persons with and without diabetes mellitus

Autor:	Kelly R. Ylitalo, Gabriel A. Benavidez, Jackson O. Griggs, Matt Asare, Beth A. Lanning, Andrew R. Meyer
Rok vydání:	2020
Předmět:	Male medicine.medical_specialty Primary health care 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires Diabetes mellitus Internal medicine medicine Humans Depressive symptoms Depression (differential diagnoses) Primary Health Care Depression business.industry 030503 health policy & services Public health Public Health Environmental and Occupational Health Peripheral Nervous System Diseases Middle Aged medicine.disease Patient Health Questionnaire Peripheral neuropathy Diabetes Mellitus Type 2 030220 oncology & carcinogenesis Quality of Life Etiology Female 0305 other medical science business
Zdroj:	Quality of Life Research. 29:3297-3304
ISSN:	1573-2649 0962-9343
DOI:	10.1007/s11136-020-02579-2
Popis:	The purpose of this study was to measure the association between peripheral neuropathy symptoms and depressive symptoms among a sample of patients with and without diabetes mellitus (DM). Patients were administered the 15-item Michigan Neuropathy Screening Instrument (MNSI) and the patient health questionnaire depression scale (PHQ-8). Patients with an MNSI score ≥ 4 were categorized as having PN and patients with a PHQ-8 score ≥ 10 were considered to have current depression. Log-binomial regression was used to analyze the relationship between PN and depressive symptoms. 406 patients were included in the final analysis. There were no statistically significant differences by diabetes status in PN symptoms (Diabetes = 61.8%; No diabetes = 55.4%; p = .20) or in depression status (Diabetes = 37.6%; No diabetes = 36.6%; p = .83). After adjustment for covariates, PN was associated with depression (aRR = 4.46; 95% CI 2.91,6.85) independent of diabetes status. PN symptoms may be common among aging persons even in the absence of DM. Past literature and our study demonstrate that PN and depression are closely associated. More work is needed to understand the etiology and potential utility of intervention for depression symptoms among patients with neuropathy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40065071b43923eff34dbe0c3c6e29e6 https://doi.org/10.1007/s11136-020-02579-2 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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