Fluocinolone acetonide (0.19 mg) intravitreal implant reduces treatment burden and improves practice resource utilisation for patients with diabetic macular oedema
Autor: | Christopher D. Riemann, Matthew Byun, James M. Osher |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Intraocular pressure vision Visual acuity genetic structures medicine.medical_treatment 03 medical and health sciences 0302 clinical medicine Quality of life Fluocinolone acetonide lcsh:Ophthalmology Ophthalmology medicine Glaucoma surgery macula 030212 general & internal medicine Original Research business.industry Treatment burden eye diseases Diabetic macular oedema lcsh:RE1-994 030221 ophthalmology & optometry Implant medicine.symptom business treatment medical medicine.drug |
Zdroj: | BMJ Open Ophthalmology BMJ Open Ophthalmology, Vol 5, Iss 1 (2020) |
ISSN: | 2397-3269 |
Popis: | ObjectivePatients with diabetic macular oedema (DME) are known to have significantly greater medical treatment burden than patients with non-DME. Frequent injections and office visits can have a substantial impact on patient adherence and quality of life. This analysis assesses the impact of the 0.19 mg fluocinolone acetonide (FAc) implant (or injection) on treatment burden and practice resource utilisation in patients with DME.Methods and analysisThis study is a single-centre retrospective chart review of 30 eyes (23 patients) that received a single FAc implant. Data was collected for a 12-month period pre-injection and post-injection of the FAc implant. Primary outcomes included the frequency of injections and ophthalmology office visits. Secondary outcomes included visual acuity (VA), intraocular pressure (IOP) and central subfield thickness (CSFT).ResultsThe injection frequency significantly decreased from one injection every 2.6 months pre-injection to one injection every 8.8 months post-injection of the FAc implant (pConclusionsThe FAc implant significantly decreased the treatment burden and improved practice resource utilisation while maintaining or improving VA and CSFT. IOP events were mostly well-controlled with drops and no eyes required incisional glaucoma surgery. |
Databáze: | OpenAIRE |
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