Symptoms of hypertrophic cardiomyopathy, with special emphasis on syncope and postprandial exacerbation of symptoms
| Autor: | Astrid E. Fletcher, Athanase Dritsas, F.A.C.C. Celia M. Oakley M.D., F.A.C.C. Petros Nihoyannopoulos M.D., Eftichia Sbarouni, M.R.C.P.I. David M. Gilligan M.D. |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Cardiomyopathy Dilated Male medicine.medical_specialty Adolescent Exacerbation Heart disease Coronary Disease Severity of Illness Index Syncope Angina Pectoris Angina Coronary artery disease Eating Surveys and Questionnaires Internal medicine Idiopathic dilated cardiomyopathy medicine Humans Prospective Studies Exercise Aged Presyncope business.industry Hypertrophic cardiomyopathy Dilated cardiomyopathy General Medicine Cardiomyopathy Hypertrophic Middle Aged medicine.disease Food Electrocardiography Ambulatory Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Clinical Cardiology. 19:371-378 |
| ISSN: | 1932-8737 0160-9289 |
| DOI: | 10.1002/clc.4960190509 |
| Popis: | We undertook a prospective study of the symptoms of hypertrophic cardiomyopathy with the aim of profiling symptomatic morbidity in detail, determining the prevalence of anxiety and depression, and describing the prevalence and associations of syncope and postprandial symptom exacerbation. A questionnaire was administered to consecutive outpatients; 70 with hypertrophic cardiomyopathy, 43 with coronary artery disease, 32 with idiopathic dilated cardiomyopathy, and to 40 normal subjects. Hypertrophic cardiomyopathy patients underwent exercise testing, echocardiography, and Holter monitoring. Hypertrophic cardiomyopathy patients had a high frequency of cardiac symptoms and, on average, had a level of symptomatic morbidity equivalent to that of chronic stable angina and dilated cardiomyopathy. There was no evidence for an excess of anxiety (14%) or depression (6%) in patients with hypertrophic cardiomyopathy. Syncope and presyncope, especially provoked by exertion or posture change, were characteristic and common symptoms in hypertrophic cardiomyopathy. A history of syncope was associated with an abnormal blood pressure response to exercise in over 50% of cases that may be the mechanism of syncope in some. Postprandial exacerbation of symptoms occurred in over one-third of hypertrophic cardiomyopathy patients, half of coronary disease patients, and infrequently in dilated cardiomyopathy. Hypertrophic cardiomyopathy patients with postprandial symptoms had a greater frequency of angina, were more symptomatic, and had a reduced exercise capacity, suggesting that postprandial symptoms are a marker for more severe disease. |
| Databáze: | OpenAIRE |
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