Synthesis and Antimicrobial Activity of 4-S-Methyl-1,3,4-Oxadiazole Derivatives of Some Natural Amino Acids Bearing Secondary Quaternary Ammonium Salt Moieties
| Autor: | Adli Djallal Eddine, Daoudi Sofiane, Benaissa Tahar, Ali Othman Adil |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
antimicrobial activity Chemistry Materials Science (miscellaneous) General Chemical Engineering Science Salt (chemistry) General Chemistry Carbon-13 NMR Antimicrobial In vitro Amino acid quaternary ammonium salts Acetic acid chemistry.chemical_compound 1 3 4-oxadiazole Organic chemistry 1 3 4 oxadiazole derivatives Ammonium QD1-999 amino acid |
| Zdroj: | Orbital: The Electronic Journal of Chemistry, Vol 10, Iss 7, Pp 482-488 (2018) |
| ISSN: | 1984-6428 |
| Popis: | Secondary quaternary ammonium salts (QAS) derived from three natural amino acids (L-Leucine, L-Phenylalanine and L-Methionine) bearing 1,3,4-oxadiazole and acetic acid moieties have been synthesized and characterized by IR, 1H and 13C NMR. All the synthesized compounds were evaluated for their preliminary in vitro antibacterial and antifungal activity against different bacterial and fungal strains. All the synthesized compounds showed varying degrees of inhibition against the tested microorganisms. DOI: http://dx.doi.org/10.17807/orbital.v10i7.990 |
| Databáze: | OpenAIRE |
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