Transient decreased retinol serum levels in children with pneumonia and acute phase response
| Autor: | Virginia Resende Silva Weffort, Daniel Ferreira da Cunha, Alceu Afonso Jordão, Selma Freire de Carvalho da Cunha, Kellen C. K. Barbosa |
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| Jazyk: | portugalština |
| Rok vydání: | 2011 |
| Předmět: |
Male
Vitamin medicine.medical_specialty Urinary system Nutritional Status Gastroenterology Statistics Nonparametric chemistry.chemical_compound Internal medicine medicine Humans Acute-Phase Reaction Vitamin A Vitamin A Deficiency business.industry Albumin Retinol Acute-phase protein Pneumonia Recovery of Function Anthropometry medicine.disease chemistry Case-Control Studies Child Preschool Pediatrics Perinatology and Child Health Immunology Female Hemoglobin business VITAMINA A (DEFICIÊNCIA) |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | Objective: To compare serum retinol levels in preschool children during an episode of pneumonia and 45 days after the resolution of the infection. Methods: The study was conducted with preschool children without any infection (control group, n = 9) or children hospitalized for pneumonia (n = 12), who were evaluated soon after hospitalization (phase 1) and 45 days later (phase 2). Nutritional assessment included anthropometric measurements, a food questionnaire, and laboratory blood routine examination, including urinary and serum retinol levels. Paired Student t or Mann-Whitney tests were used as required. Results: Food intake was similar between groups. Blood hemoglobin and serum sodium and albumin decreased during phase 1, while there were higher C-reactive protein serum values. Urinary retinol levels remained unchanged whereas serum retinol increased significantly after pneumonia recovery. Conclusion: During the course of pneumonia, children had transient decrease in serum levels of vitamin A, an epiphenomenon of the acute phase response. |
| Databáze: | OpenAIRE |
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