Hand-Schueller-Christian disease with occult diabetes insipidus, cardiac failure and renal dysfunction
| Autor: | Hiroaki Aoyama, Kazuyasu Endo, Tokihisa Kimura, Masahiro Ohta, Kaoru Yoshinaga, Hirofumi Osaki, Masaru Shoji, Kazutoshi Sato, Keishi Abe, Tadasu Yamamoto, Minoru Inoue, Kozo Ota |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty endocrine system diseases Vasopressins Cardiac Output Low urologic and male genital diseases Gastroenterology Blood Urea Nitrogen Polyuria Eosinophilic granuloma Internal medicine Diabetes mellitus medicine Humans Hand–Schüller–Christian disease Deamino Arginine Vasopressin business.industry General Medicine Acute Kidney Injury Middle Aged Water-Electrolyte Balance medicine.disease female genital diseases and pregnancy complications Surgery Histiocytosis Langerhans-Cell Vincristine Diabetes insipidus Urine osmolality medicine.symptom Thyroid function business Polydipsia Atrial Natriuretic Factor Diabetes Insipidus hormones hormone substitutes and hormone antagonists |
| Zdroj: | Japanese Journal of Medicine. 29:405-410 |
| ISSN: | 1881-123X 0021-5120 |
| DOI: | 10.2169/internalmedicine1962.29.405 |
| Popis: | A 60-year-old man was diagnosed as Hand-Schüller-Christian disease due to the triad of exophthalmus, decalcification of the bone, and diabetes insipidus. He had xanthogranuloma on the face and a nuchal region, and unusual complications of ADH-resistant diabetes insipidus due to renal dysfunction, and chronic cardiac failure. Urine osmolality was hypotonic, but urine volume was within the normal limit, despite the presence of central diabetes insipidus. Hypophyseal, adrenal and thyroid function were not remarkable. The skin biopsy showed the infiltration of eosinophilic granuloma cells. Treatment with vincristine was effective to regress the xanthogranuloma. Diabetes insipidus was not treated because of the absence of polyuria and polydipsia. |
| Databáze: | OpenAIRE |
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