Dynamic Functional Connectivity States Between the Dorsal and Ventral Sensorimotor Networks Revealed by Dynamic Conditional Correlation Analysis of Resting-State Functional Magnetic Resonance Imaging
| Autor: | Haris I. Sair, Maleeha Syed, Martin A. Lindquist, Ann S. Choe, Brian Caffo, Shruti Agarwal, Sachin K. Gujar, Jay J. Pillai |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Dorsum Rest Models Neurological 050105 experimental psychology Young Adult 03 medical and health sciences 0302 clinical medicine Neural Pathways Image Processing Computer-Assisted medicine Cluster Analysis Humans 0501 psychology and cognitive sciences Dynamic functional connectivity Physics Brain Mapping medicine.diagnostic_test Resting state fMRI General Neuroscience Functional connectivity 05 social sciences Brain Middle Aged Magnetic Resonance Imaging Oxygen Resting state functional magnetic resonance imaging Nonlinear Dynamics Correlation analysis Sensorimotor network Female Functional magnetic resonance imaging Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Brain Connectivity. 7:635-642 |
| ISSN: | 2158-0022 2158-0014 |
| Popis: | Functional connectivity in resting-state functional magnetic resonance imaging (rs-fMRI) has received substantial attention since the initial findings of Biswal et al. Traditional network correlation metrics assume that the functional connectivity in the brain remains stationary over time. However, recent studies have shown that robust temporal fluctuations of functional connectivity among as well as within functional networks exist, challenging this assumption. In this study, these dynamic correlation differences were investigated between the dorsal and ventral sensorimotor networks by applying the dynamic conditional correlation model to rs-fMRI data of 20 healthy subjects. k-Means clustering was used to determine an optimal number of discrete connectivity states (k = 10) of the sensorimotor system across all subjects. Our analysis confirms the existence of differences in dynamic correlation between the dorsal and ventral networks, with highest connectivity found within the ventral motor network. |
| Databáze: | OpenAIRE |
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