Cytogenetic testing for therapeutic indication in cancer
| Autor: | Yelina Noskina, Suneel D. Mundle |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Chromosome Aberrations
Oncology Functional role medicine.medical_specialty Cancer Breast Neoplasms Biology Molecular diagnostics medicine.disease Leukemia Lymphocytic Chronic B-Cell Pathology and Forensic Medicine Breast cancer Her 2 neu Leukemia Myelogenous Chronic BCR-ABL Positive Internal medicine Cytogenetic Analysis Immunology Genetics medicine Humans Molecular Medicine Molecular Biology Chronic myelogenous leukemia |
| Zdroj: | Expert Review of Molecular Diagnostics. 5:23-29 |
| ISSN: | 1744-8352 1473-7159 |
| Popis: | The association of cytogenetic abnormalities with cancer is well established. However, due to the historic lack of specific insight into the functional role of these anomalies, they have mostly served as diagnostic and/or prognostic indicators. Recent developments in chronic myelogenous leukemia and breast cancer have raised hopes for specific cytogenetic alterations to serve as therapeutic targets. This article reviews the aid provided by molecular diagnostics in these exciting developments in the cancer arena. |
| Databáze: | OpenAIRE |
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