Intravascular lymphoma involving the central and peripheral nervous systems in a dog
| Autor: | Amy S. Kapatkin, Charles H. Vite, Patricia M. McManus, Juliene L. Throop, William W. Bush, Tom Van Winkle |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
Vincristine Pathology medicine.medical_specialty Ataxia Lymphoma medicine.medical_treatment Central Nervous System Neoplasms Death Sudden Dogs Paraparesis Prednisone Peripheral Nervous System Neoplasms Biopsy Antineoplastic Combined Chemotherapy Protocols medicine Animals Dog Diseases Small Animals Chemotherapy medicine.diagnostic_test business.industry Antemortem Diagnosis Hyperesthesia Magnetic resonance imaging Magnetic Resonance Imaging Thrombocytopenia Vascular Neoplasms medicine.symptom business Tomography X-Ray Computed medicine.drug |
| Zdroj: | Journal of the American Animal Hospital Association. 39(1) |
| ISSN: | 0587-2871 |
| Popis: | A 5-year-old, castrated male mixed-breed dog was presented for paraparesis, ataxia, hyperesthesia, and thrombocytopenia of 5 months’ duration and recurrent seizures during the preceding 2 weeks. Multifocal neurological, ophthalmological, pulmonary, and cardiac diseases were identified. Magnetic resonance imaging and cerebrospinal fluid analysis supported a tentative diagnosis of neoplastic or inflammatory disease. A computed tomography-guided biopsy provided both cytopathological and histopathological evidence of intravascular lymphoma. The disease progressed despite chemotherapy with prednisone, L-asparginase, and vincristine. Postmortem histopathological examinations suggested intravascular lymphoma in the central and peripheral nervous systems as well as in multiple other organ systems. This is the first description of an antemortem diagnosis and treatment of intravascular lymphoma involving the central nervous system of a dog. |
| Databáze: | OpenAIRE |
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