Total phenolic content and antioxidant and anticholinesterase activities of medicinal plants from the State’s Cocó Park (Fortaleza-CE, Brazil)
Autor: | Marcus Vinicius Ferreira da Silva, Francisco Flávio da Silva Lopes, Gilson Araújo Fontenele, Selene Maia de Morais, Victor Borges Fernandes, Daniela Ribeiro Alves |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Atividade antioxidante
Antioxidant DPPH Atividade anticolinesterásica Plantas medicinales medicine.medical_treatment Plantas medicinais 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Medicinal plants Antioxidant activity Parque Estadual do Cocó medicine Coco Mangifera 030304 developmental biology General Environmental Science 0303 health sciences biology Traditional medicine Anticholinesterase activity Ceiba Chemistry Anacardium Terminalia biology.organism_classification Parque Estatal Cocó Actividad anticolinesterasa Cocó State Park General Earth and Planetary Sciences Actividad antioxidante 030217 neurology & neurosurgery |
Zdroj: | Research, Society and Development; Vol. 10 No. 5; e7510514493 Research, Society and Development; Vol. 10 Núm. 5; e7510514493 Research, Society and Development; v. 10 n. 5; e7510514493 Research, Society and Development Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
ISSN: | 2525-3409 |
Popis: | The State’s Cocó Park in the city of Fortaleza-CE present mainly a mangrove flora and include landscape and medicinal plants. The aim of this study is determining the total phenol content, antioxidant activity against the free radical DPPH and the inhibition of the enzyme acetylcholinesterase (AChE) in ethanolic extracts of 30 medicinal plants and thus assess which plants have potential against Alzheimer's Disease. The plants rich in phenolic compounds with amounts ranging from 297.46 ± 26.94 to 599.30 ± 17.08 mg GAE/g plant extract, which showed greater antioxidant activities (with IC50 against DPPH radical from 3.44 ± 0.16 to 3.73 ± 0.12 µg mL-1) and higher acetylcholinesterase inhibiting power (IC50 < 20 μg mL-1) were Anacardium occidentale, Ceiba pentandraLaguncularia racemosa, Mangifera indica, Myracrodrum urundeuva and Terminalia catappa. Then, these species and their constituents are recommended for more specific studies related to Alzheimer´s Disease. El Parque Cocó del Estado en la ciudad de Fortaleza-CE presenta principalmente una flora de manglar e incluye plantas paisajísticas y medicinales. El objetivo de este estudio es determinar el contenido total de fenol, la actividad antioxidante frente al radical libre DPPH y la inhibición de la enzima acetilcolinesterasa (AChE) en extractos etanólicos de 30 especies medicinales y así evaluar qué plantas tienen potencial contra la enfermedad de Alzheimer. Las plantas ricas en compuestos fenólicos con cantidades que van desde 297.46 ± 26.94 a 599.30 ± 17.08 mg GAE/g de extracto vegetal, que mostraron mayor actividad antioxidante (con IC50 contra el radical DPPH de 3.44 ± 0.16 a 3.73 ± 0.12 µg mL-1) y superiores El poder inhibidor de la acetilcolinesterasa (IC50 < 20 μg mL-1) fueron Anacardium occidentale, Ceiba pentandra, Lagucularia racemosa, Mangifera indica, Myracrodrum urundeuva y Terminalia catappa. Luego, estas especies y sus constituyentes se recomiendan para estudios más específicos relacionados con la enfermedad de Alzheimer. O Parque Estadual do Cocó na cidade de Fortaleza-CE apresenta uma flora principalmente constituída de manguezais e inclui plantas decorativase plantas medicinais. O objetivo deste estudo é determinar o teor de fenóis totais a atividade antioxidante contra o radical livre DPPH e a inibição da enzima acetilcolinesterase (AChE) em extratos etanólicos de 30 espécies de plantas medicinais e assim avaliar quais plantas têm potencial contra a doença de Alzheimer. As plantas ricas em compostos fenólicos com teores superiores variando de 297,46 ± 26,94 a 599,30 ± 17,08 mg GAE/g extrato vegetal, que apresentaram maiores atividades antioxidantes (com IC50 contra o radical DPPH de 3,44 ± 0,16 a 3,73 ± 0,12 µg mL-1) e poder inibidor da acetilcolinesterase (IC50 < 20 μg mL-1) foram Anacardium occidentale, Ceiba pentandra, Laguncularia racemosa, Mangifera indica, Myracrodrum urundeuva e Terminalia catappa. Então, essas espécies e seus constituintes são recomendados para estudos mais específicos relacionados à Doença de Alzheimer. |
Databáze: | OpenAIRE |
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