Significance of Nitric Oxyde Saliva Concentration of the Patients with Renal Failure on Hemodialysis

Autor: Nerma Resic, Azra Durak-Nalbantic, Elmedina Jahic, Faris Zvizdić, Marina Vučijak-Grgurević, Jasminko Huskić
Rok vydání: 2018
Předmět:
Zdroj: Materia Socio-Medica
ISSN: 1512-7680
Popis: Introduction: An increase in nitric oxide (NO) synthesis concentration could help alleviate some pathological changes directly related to uremia. Aim: To investigate the concentration of nitric oxide in saliva of patients with terminal stage of chronic renal failure on hemodialysis and to investigate the effect of hemodialysis on concentration of nitric oxide in saliva of the patients with terminal stage of chronic renal failure on hemodialysis. Material and Methods: The study had a prospective character and included 60 respondents of both sexes, at age between 20 and 60 years. The control group included 30 healthy volunteers of both sexes (15 men and 15 women) of the same age, who were based on subjective and objective health status without any manifestations of pathophysiological changes. The group of patients with terminal stage of chronic renal failure on hemodialysis involved 30 patients of both sexes (15 men and 15 women). Inclusion criteria: hemodialysis duration more than 6 months and age between 20 and 60 years. Results: The amount of non-stimulated saliva collected during 15 minutes in patients with chronic renal failure was lower by 31.3% compared to the control group of healthy subjects (p
Databáze: OpenAIRE