The role of changes in maximum standardized uptake value of FDG PET-CT for post-treatment surveillance in patients with head and neck squamous cell carcinoma treated with chemoradiotherapy: preliminary findings
| Autor: | Munetaka Matoba, Kiyotaka Oota, Tamaki Kondo, Hisao Tonami, Hiroyuki Tuji, Yuzo Shimode |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Standardized uptake value Disease-Free Survival 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 Positron Emission Tomography Computed Tomography Humans Medicine Radiology Nuclear Medicine and imaging In patient Prospective Studies Aged Aged 80 and over Full Paper medicine.diagnostic_test Squamous Cell Carcinoma of Head and Neck business.industry Chemoradiotherapy General Medicine Middle Aged medicine.disease Head and neck squamous-cell carcinoma Treatment Outcome Time to recurrence Head and Neck Neoplasms Positron emission tomography 030220 oncology & carcinogenesis Carcinoma Squamous Cell Female Fdg pet ct Radiopharmaceuticals Post treatment Nuclear medicine business |
| Zdroj: | The British Journal of Radiology. 90:20150404 |
| ISSN: | 1748-880X 0007-1285 |
| DOI: | 10.1259/bjr.20150404 |
| Popis: | Objective:No clear consensus exists regarding the optimal interval and frequency of follow-up positron emission tomography (PET)-CT in patients with head and neck squamous cell carcinoma (HNSCC) treated with chemoradiotherapy (CRT). Here, we sought to clarify whether the changes in the maximum standardized uptake value (ΔSUVmax) may be a valid parameter to help decision-making for surveillance management after CRT.Methods:40 patients underwent PET-CT at pre-treatment and 3 months after CRT. Patients were followed by sequential PET-CT for 2 years after CRT. The ΔSUVmax of the primary tumour and the metastatic nodes were calculated between pre-treatment and 3 months after the CRT, and we evaluated the associations between ΔSUVmax and the manifestation of recurrence, time to recurrence and the patient survival.Results:The ΔSUVmax of the primary tumour was significantly lower for the lesions with recurrence than that for those with non-recurrence for both the primary site and the nodal site (p = 0.007, 0.02).... |
| Databáze: | OpenAIRE |
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