The potential of curcumin for treating spinal cord injury: a meta-analysis study

Autor: Mahnaz Kahuripour, Zahra Behroozi, Behnaz Rahimi, Michael R. Hamblin, Fatemeh Ramezani
Rok vydání: 2022
Předmět:
Zdroj: Nutritional neuroscience.
ISSN: 1476-8305
Popis: In this paper, we conducted a meta-analysis on the curcumin effect on functional recovery provided by the Basso, Beattie, Brenham (BBB) test for rats, and the Basso mouse scale (BMS) for mice after spinal cord injury (SCI) in animal models.Data mining was performed, and the standard mean difference (SMD) between the treated and control (untreated) groups was calculated using the STATA software. Quality control and subgroup analysis were performed.The analysis includes 24 experimental studies that showed curcumin had a strong significance in improving functional recovery after SCI (SMD = 3.38; 95% CI: 2.54-4.22;These findings suggest that daily administration of curcumin can be an effective approach to improving functional recovery after SCI.
Databáze: OpenAIRE