Long-term treatment of congestive heart failure by Captopril: hemodynamic, biological and clinical effects
| Autor: | J. M. Fauvel, Kayanakis Jg, P. Giraud, Jean-Paul Bounhoure |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Male
Cardiac Catheterization medicine.medical_specialty Mean arterial pressure Captopril Proline Hemodynamics Plasma renin activity Internal medicine Heart rate Humans Medicine Pulmonary wedge pressure Aged Heart Failure business.industry Middle Aged medicine.disease medicine.anatomical_structure Heart failure Chronic Disease Vascular resistance Cardiology Female Cardiology and Cardiovascular Medicine business Follow-Up Studies medicine.drug |
| Zdroj: | European Heart Journal. 2:75-81 |
| ISSN: | 1522-9645 0195-668X |
| DOI: | 10.1093/oxfordjournals.eurheartj.a061166 |
| Popis: | Congestive heart failure is frequently associated with an increase in peripheral resistance induced by stimulation of the renin angiotensin system and of the sympathetic nervous system. The clinical, biological and hemodynamic effects of Captopril (SQ 14225), an oral inhibitor of angiotensin converting enzyme, were measured in 20 patients with heart failure poorly controlled by digitalis,diuretics and vasodilator therapy. After two months of Captopril administration from 150 to 250 mg per day, NYHA functional class improved from 34 to 206 (P |
| Databáze: | OpenAIRE |
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