Developmental Profile and Trajectory of Neuropsychological Skills in A Child With Kabuki Syndrome: Implications for Assessment of Syndromes Associated with Intellectual Disability
| Autor: | Paul H. Lipkin, Jacqueline H. Sanz, E. Mark Mahone, Kenneth N. Rosenbaum |
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| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Developmental Disabilities Neuropsychological Tests Executive Function Arts and Humanities (miscellaneous) Intellectual Disability Adaptation Psychological Intellectual disability Developmental and Educational Psychology medicine Humans Abnormalities Multiple Longitudinal Studies Neuropsychological assessment Child Psychiatry Language Intelligence Tests medicine.diagnostic_test Intelligence quotient Mood Disorders Age Factors Neuropsychology Neuropsychological test Verbal Learning medicine.disease Hematologic Diseases Developmental disorder Psychiatry and Mental health Clinical Psychology Neuropsychology and Physiological Psychology Vestibular Diseases Face Visual Perception Female Cognition Disorders Psychology Kabuki syndrome Psychomotor Performance Executive dysfunction |
| Zdroj: | The Clinical Neuropsychologist. 24:1181-1192 |
| ISSN: | 1744-4144 1385-4046 |
| Popis: | Kabuki syndrome (KS) is a rare genetic syndrome involving dysmorphic facial features, and reports of intellectual disability (ID). We examined the developmental trajectory of neuropsychological skills in a child with KS (seen at ages 4, 6, 7, 9, and 11). Examination of raw and age-corrected standard scores suggests that language-based skills developed appropriately, but visually based skills slowed and reached a plateau. Executive dysfunction and mood symptoms were also observed. While ID is described as a core feature of KS, some patients may not meet diagnostic criteria for ID, and may be better described as having specific deficits in nonverbal skills. Longitudinal neuropsychological assessment of children with KS and other syndromes associated with ID is warranted to understand the true prevalence of ID versus isolated cognitive impairments. |
| Databáze: | OpenAIRE |
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