Extracellular Matrix-Mimetic Peptide Scaffolds Prolonged the Hypothermic Preservation of Stem Cells for Storage and Transportation
| Autor: | Kun Liu, Lei Wang, Dongdong Li, Shaoduo Yan, Jiayao Li, Xiaoyang Yi, Yunfeng Sun, Yanhong Li, Xuan Zhang, Fengying Qi, Yizhe Zheng, Zixin He, Donggen Wang, Yuyuan Ma, Jun Liang, Qiuxia Fu |
|---|---|
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | ACS Applied Materials & Interfaces. 15:684-696 |
| ISSN: | 1944-8252 1944-8244 |
| DOI: | 10.1021/acsami.2c20456 |
| Popis: | Encouraging advances in both regenerative medicine and tissue engineering with stem cells require a short-term preservation protocol to provide enough time for quality control or the transportation of cell products from manufacturing facilities to clinical destinations. The hypothermic preservation of stem cells under refrigerated conditions (2-8 °C) in their specific culture medium provides an alternative and low-cost method for cryopreservation or commercial preservation fluid for short-term storage. However, most stem cells are vulnerable to hypothermia, which might result in cell damage from the cooling process and the lack of extracellular matrix (ECM). Herein, we report a peptide scaffold cell-culture-medium additive for mimicking |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|