Prevalence, mechanisms and impact of residual patency and device-related thrombosis following left atrial appendage occlusion: a computed tomography analysis
| Autor: | Lluis Asmarats, Xavier Millán, Antonio Serra, Victor Agudelo, Chi-Hion Li, Dabit Arzamendi, Abdel-Hakim Moustafa |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Leak Septal Occluder Device medicine.medical_treatment Computed tomography Left atrial appendage occlusion Clinical Research Left atrial Internal medicine Atrial Fibrillation MSCT Prevalence medicine Humans Atrial Appendage atrial fibrillation Thrombus medicine.diagnostic_test business.industry Thrombosis medicine.disease Peripheral Treatment Outcome LAA closure Embolism Cardiology Tomography X-Ray Computed Cardiology and Cardiovascular Medicine business Echocardiography Transesophageal |
| Zdroj: | EuroIntervention r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname |
| ISSN: | 1969-6213 1774-024X |
| Popis: | BACKGROUND: Cardiac computed tomography angiography (CCTA) appears to be an appropriate imaging technique for device surveillance after left atrial appendage occlusion (LAAO). However, the available experience is limited. AIMS: The aim of this study was to determine the prevalence, mechanisms and clinical impact of left atrial appendage (LAA) patency and device-related thrombosis (DRT) following LAAO utilising a novel CCTA-based classification. METHODS: Consecutively enrolled patients who underwent LAAO with an AMPLATZER device were followed up with CCTA. Mechanisms and frequency of residual patency were evaluated and correlated with clinical events. Atrial-side device thrombus, device positioning and presence of signs of device stability were also analysed. RESULTS: A total of 137 patients were included. LAA patency was observed in 56.9% (n=78). Mechanisms and frequency of patency were: malapposition of proximal segment of the device lobe (55.1%), peri-device leak (PDL, 34.6%) and fabric permeability (5.8%). Lobe-LAA axis misalignment was the only independent predictor of device patency after LAAO (HR 38.3, 95% CI: 13.6-107.0; p |
| Databáze: | OpenAIRE |
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