| Autor: |
Beverly A. Mock, Jing Huang, Peter Ordentlich, Ola Landgren, Adriana Zingone, Maxwell P. Lee, W. Michael Kuehl, Jin-Qiu Chen, Elena Leon, Nicholas Watson, Daniel Connors, Snehal Gaikwad, Shuling Zhang, Joy Gary, Ke Zhang, Jyoti Patel, Wendy DuBois, Benjamin J. Gamache, Aleksandra M. Michalowski, John K. Simmons |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1535-7163.c.6539409 |
| Popis: |
Cancer treatments often require combinations of molecularly targeted agents to be effective. mTORi (rapamycin) and HDACi (MS-275/entinostat) inhibitors have been shown to be effective in limiting tumor growth, and here we define part of the cooperative action of this drug combination. More than 60 human cancer cell lines responded synergistically (CIin vivo. Mol Cancer Ther; 16(9); 2008–21. ©2017 AACR. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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