FMDV 3A Antagonizes the Effect of ANXA1 to Positively Modulate Viral Replication

Autor: XuSheng Ma, KeShan Zhang, ZhiKuan Luo, XiaoFeng Nian, S. K. Mohiuddin Choudhury, ZiXiang Zhu, Rui Song, JingJing Pei, YanLi Huo, YuanYuan Li, Fan Yang, WeiJun Cao, HuiSheng Liu, XiangTao Liu, HaiXue Zheng
Rok vydání: 2022
Předmět:
Zdroj: Journal of Virology. 96
ISSN: 1098-5514
0022-538X
DOI: 10.1128/jvi.00317-22
Popis: The RIG-I-like receptor signaling pathway is crucial for producing type I interferon (IFN-I) against RNA viruses. The present study observed that viral infection increased annexin-A1 (ANXA1) expression, and ANXA1 then promoted RNA virus-induced IFN-I production. Compared to ANXA1 wild-type cells, ANXA1
Databáze: OpenAIRE