Graves' Disease Presenting as Urticaria
| Autor: | Abdulrahman Murshid, Abdullah M AlHossan, Mohammed Gaffar Mohammed, Mohammed A Al Rushud, Saud Almuammar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Graves' disease Disease Dermatology 030204 cardiovascular system & hematology allergic reaction Allergy/Immunology 03 medical and health sciences chemistry.chemical_compound urticaria 0302 clinical medicine immune system diseases parasitic diseases medicine Internal Medicine skin and connective tissue diseases Autoimmune disease Angioedema business.industry Thyroid General Engineering medicine.disease Pathophysiology Carbimazole medicine.anatomical_structure chemistry medicine.symptom business 030217 neurology & neurosurgery Histamine medicine.drug graves-basedow |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Graves' disease (GD) is an autoimmune disease that is characterized by the presence of antibodies targeting the thyroid gland. Commonly, the disease presents with symptoms of thyrotoxicosis such as sweating, tremors, and weight loss; less frequently, patients with GD might also have urticaria. Urticaria is clinically defined as the presence of wheals, angioedema, or both. While its pathophysiology is not completely understood, urticaria is believed to be an immune-mediated response activating mast cells, leading to the release of histamine and cytokines. Although the association between urticaria and GD is well established, it is uncommon for GD patients to present with urticaria as their sole complaint. In this paper, we present a case of a previously healthy patient who originally presented to the dermatology clinic with urticaria alone; however, she developed thyrotoxic symptoms soon after. Furthermore, her treatment was complicated by developing an allergic reaction to carbimazole. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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