Automatic detection of valve events by epicardial accelerometer allows estimation of the left ventricular pressure trace and pressure–displacement loop area
| Autor: | Ole Jakob Elle, Ali Wajdan, Magnus Reinsfelt Krogh, Per Steinar Halvorsen, Manuel Villegas-Martinez, Espen W. Remme |
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| Rok vydání: | 2020 |
| Předmět: |
Correlation coefficient
0206 medical engineering Cardiology Hemodynamics lcsh:Medicine 02 engineering and technology 030204 cardiovascular system & hematology Accelerometer Signal Displacement (vector) Article Ventricular Function Left 03 medical and health sciences 0302 clinical medicine Dogs Heart Rate Accelerometry Ventricular Pressure Animals Closing (morphology) lcsh:Science Physics Multidisciplinary lcsh:R Health care 020601 biomedical engineering Heart Valves Loop (topology) Ventricular pressure lcsh:Q Biomedical engineering |
| Zdroj: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020) |
| ISSN: | 2045-2322 |
| Popis: | Measurements of the left ventricular (LV) pressure trace are rarely performed despite high clinical interest. We estimated the LV pressure trace for an individual heart by scaling the isovolumic, ejection and filling phases of a normalized, averaged LV pressure trace to the time-points of opening and closing of the aortic and mitral valves detected in the individual heart. We developed a signal processing algorithm that automatically detected the time-points of these valve events from the motion signal of a miniaturized accelerometer attached to the heart surface. Furthermore, the pressure trace was used in combination with measured displacement from the accelerometer to calculate the pressure–displacement loop area. The method was tested on data from 34 animals during different interventions. The accuracy of the accelerometer-detected valve events was very good with a median difference of 2 ms compared to valve events defined from hemodynamic reference recordings acquired simultaneously with the accelerometer. The average correlation coefficient between the estimated and measured LV pressure traces was r = 0.98. Finally, the LV pressure–displacement loop areas calculated using the estimated and measured pressure traces showed very good correlation (r = 0.98). Hence, the pressure–displacement loop area can be assessed solely from accelerometer recordings with very good accuracy. |
| Databáze: | OpenAIRE |
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