Management of refractory pain in hospitalized adolescents with sickle cell disease: changing from intravenous opioids to continuous infusion epidural analgesia
| Autor: | Claudia Venable, Jennifer Schmidt, Anne James-Herry, Erin Rosenberg, Carlton Dampier, Tamara New, Ifeyinwa Osunkwo, Laura Fraser |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Adolescent Hospitalized Anemia Analgesic Administration Oral Disease Anemia Sickle Cell Refractory Interquartile range medicine Humans Child Infusions Intravenous Retrospective Studies Morphine business.industry Retrospective cohort study Hematology medicine.disease Surgery Pain Intractable Analgesia Epidural Analgesics Opioid Treatment Outcome Oncology Opioid Anesthesia Pediatrics Perinatology and Child Health Female business medicine.drug |
| Zdroj: | Journal of pediatric hematology/oncology. 36(6) |
| ISSN: | 1536-3678 |
| Popis: | Background Prolonged hospitalizations for sickle cell disease painful episodes are not uncommon, as analgesic options are often suboptimal. Observations Seven patients (15.4 ± 3.7 y, 6 females) were treated with epidural analgesia for refractory pain. The median duration of epidural catheter placement was 4 days (interquartile range, 3 to 6 d). Mean pain scores changed from 6.8 ± 2.7 to 4.8 ± 2.2, whereas mean daily parenteral opioid requirements changed from 79.7 ± 100.4 to 13.0 ± 13.1 mg of morphine equivalents. Conclusion Continuous epidural analgesia is an alternative to continuing intravenous opioids in sickle cell disease patients with refractory pain, and may reduce opioid-related side effects and facilitate transition to oral analgesics. |
| Databáze: | OpenAIRE |
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