Phosphatidylinositol-4-phosphate joins the dance of plant autophagosome formation

Autor: Rodrigo Enrique Gomez, Julie Castets, Josselin Lupette, Clément Chambaud, Jérôme Joubès, Amélie Bernard
Jazyk: angličtina
Předmět:
Zdroj: Autophagy. 19(5):1609-1610
ISSN: 1554-8635
1554-8627
DOI: 10.1080/15548627.2022.2132042
Popis: In plants, macroautophagy/autophagy is a key mechanism that contributes to their ability to cope with a wide range of environmental constraints such as drought, nutrient starvation or pathogen resistance. Nevertheless, the molecular mechanisms of plant autophagy, and notably that of autophagosome formation, remain poorly understood. As the starting point of our recent paper, we considered the potential functional contribution of lipids in the numerous membrane-remodeling steps involved in this process. By combining biochemistry, genetics, cell biology and high-resolution 3D imaging, we unraveled the function of the lipid phosphatidylinositol-4-phosphate (PtdIns4P) in autophagy in
Databáze: OpenAIRE