Extracting diffusion tensor fractional anisotropy and mean diffusivity from 3-direction DWI scans using deep learning
| Autor: | Sohil H. Patel, Eric Aliotta, Hamidreza Nourzadeh |
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| Rok vydání: | 2020 |
| Předmět: |
Physics
Single voxel business.industry Deep learning Thermal diffusivity Convolutional neural network Magnetic Resonance Imaging 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Nuclear magnetic resonance Deep Learning Diffusion Magnetic Resonance Imaging Diffusion Tensor Imaging Neuroimaging Multilayer perceptron Fractional anisotropy Anisotropy Humans Radiology Nuclear Medicine and imaging Artificial intelligence business 030217 neurology & neurosurgery Diffusion MRI |
| Zdroj: | Magnetic resonance in medicineREFERENCES. 85(2) |
| ISSN: | 1522-2594 |
| Popis: | Purpose To develop and evaluate machine-learning methods that reconstruct fractional anisotropy (FA) values and mean diffusivities (MD) from 3-direction diffusion MRI (dMRI) acquisitions. Methods Two machine-learning models were implemented to map undersampled dMRI signals with high-quality FA and MD maps that were reconstructed from fully sampled DTI scans. The first model was a previously described multilayer perceptron (MLP), which maps signals and FA/MD values from a single voxel. The second was a convolutional neural network U-Net model, which maps dMRI slices to full FA/MD maps. Each method was trained on dMRI brain scans (N = 46), and reconstruction accuracies were compared with conventional linear-least-squares (LLS) reconstructions. Results In an independent testing cohort (N = 20), 3-direction U-Net reconstructions had significantly lower absolute FA error than both 3-direction MLP (U-Net3-dir : 0.06 ± 0.01 vs. MLP3-dir : 0.08 ± 0.01, P .1). Conclusion The proposed U-Net model reconstructed FA from 3-direction dMRI scans with improved accuracy compared with both a previously described MLP approach and LLS fitting from 6-direction scans. The MD reconstruction accuracies did not differ significantly between reconstructions. |
| Databáze: | OpenAIRE |
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