Mediterranean spotted fever: clinical, laboratory and epidemiological features of 199 cases

Autor: Didier Raoult, Hervé Chaudet, Hervé Gallais, Paul Casanova, Pierre J. Weiller, André Chagnon
Rok vydání: 1986
Předmět:
Zdroj: The American journal of tropical medicine and hygiene. 35(4)
ISSN: 0002-9637
Popis: Most previous studies of Mediterranean spotted fever (MSF) have included cases that either were not laboratory-confirmed or were confirmed by the Weil-Felix test. The authors report the detailed clinical, laboratory and epidemiological features of 199 serologically-confirmed cases of MSF (by microimmunofluorescence). This work demonstrates that the disease is difficult to diagnose, especially at the beginning; that it can be fatal (2.5% of cases); and that a rapid and specific diagnosis is necessary to identify atypical cases. Epidemiological features such as season (summer essentially), presence of a dog, and travel in an endemic area (the Mediterranean Basin) are important in the diagnosis. In such cases fever associated with rash have to be considered and treated as MSF.
Databáze: OpenAIRE