A comparison of PGC-1α mRNA and protein expression in response to 1-week endurance training on alternate days or 4 consecutive days
| Autor: | Liping Huang, Ya-Li Wang, Shi Zhou, Min Yao, Allan J Davie |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Physiology Endocrinology Diabetes and Metabolism Protein expression Running Rats Sprague-Dawley Gastrocnemius muscle Downregulation and upregulation Endurance training Physiology (medical) Internal medicine Coactivator medicine Animals RNA Messenger Muscle Skeletal Receptor Messenger RNA Nutrition and Dietetics business.industry General Medicine Adaptation Physiological Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Up-Regulation Endocrinology Physical Endurance medicine.symptom business Muscle Contraction Transcription Factors Muscle contraction |
| Zdroj: | Applied Physiology, Nutrition, and Metabolism. 40:1210-1213 |
| ISSN: | 1715-5320 1715-5312 |
| DOI: | 10.1139/apnm-2015-0222 |
| Popis: | To understand the molecular mechanisms of adaptation to different training protocols, this study compared the effects of 4 sessions of 90 min treadmill exercise on alternate days or consecutive days in 1 week on messenger RNA (mRNA) and protein expression of proliferator-activated receptor-γ coactivator 1-α in rat gastrocnemius muscle. The mRNA significantly increased by 25.8-fold after alternate-day and 10.1-fold after consecutive-day training, while the protein showed no significant cumulative effect, 1.5–1.7-fold above baseline, in the 2 protocols. |
| Databáze: | OpenAIRE |
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