Long-range motor performance changes in levodopa-treated patients with Parkinson's disease
| Autor: | Jackson H. Birdsong, Alexander S. McKinney |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Male
Levodopa medicine.medical_specialty Time Factors Parkinson's disease business.industry Levodopa therapy Parkinson Disease Disease Middle Aged medicine.disease Motor function Dihydroxyphenylalanine Physical medicine and rehabilitation Evaluation Studies as Topic Motor Skills Dopamine medicine Humans Female In patient Neurology (clinical) business medicine.drug |
| Zdroj: | Neurology. 24:107-107 |
| ISSN: | 1526-632X 0028-3878 |
| DOI: | 10.1212/wnl.24.2.107 |
| Popis: | A precise measurement of motor function, Methods-Time Measurement, was used to analyze motor performance in patients with Parkinson9s disease receiving levodopa therapy. The data indicate an initial improvement, in all motions of the upper extremity, that reaches a maximum and then slowly declines over a period of years. Thus it appears that Parkinson9s disease continues to advance despite treatment with L-dopa. It is unlikely that a biochemical disorder is the basis of the illness. More likely a basic neuropathologic disorder is responsible for inducing dopamine deficiency, so that arresting the condition will depend on identification and correction of this more fundamental defect. |
| Databáze: | OpenAIRE |
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