A novel implanted device to wirelessly record and analyze continuous intracranial canine EEG
| Autor: | Gregory A. Worrell, Beverly K. Sturges, Andrew B. Gardner, W. Douglas Sheffield, Kathryn A. Davis, Kent W. Leyde, Charles H. Vite, Brian Litt, Vanessa Ruedebusch |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Male
Response to therapy Electroencephalography Article Epilepsy Seizure onset Dogs Animals Telemetry Medicine Epilepsy surgery Wakefulness Implanted device Monitoring Physiologic medicine.diagnostic_test business.industry medicine.disease Electrodes Implanted Electrophysiology Neurology Anesthesia Anticonvulsants Female Neurology (clinical) business Neuroscience Algorithms |
| Zdroj: | Epilepsy Research. 96:116-122 |
| ISSN: | 0920-1211 |
| Popis: | We present results from continuous intracranial electroencephalographic (iEEG) monitoring in 6 dogs with naturally occurring epilepsy, a disorder similar to the human condition in its clinical presentation, epidemiology, electrophysiology and response to therapy. Recordings were obtained using a novel implantable device wirelessly linked to an external, portable real-time processing unit. We demonstrate previously uncharacterized intracranial seizure onset patterns in these animals that are strikingly similar in appearance to human partial onset epilepsy. We propose: (1) canine epilepsy as an appropriate model for testing human antiepileptic devices and new approaches to epilepsy surgery, and (2) this new technology as a versatile platform for evaluating seizures and response to therapy in the natural, ambulatory setting. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect