Impact of central venous pressure on the mortality of patients with sepsis-related acute kidney injury: a propensity score-matched analysis based on the MIMIC IV database
| Autor: | Huo, Yan, Wang, Xinrui, Li, Bo, Rello Condomines, Jordi, Kim, Won-Young, Wang, Xiaoting, Hu, Zhenjie |
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| Přispěvatelé: | Institut Català de la Salut, [Huo Y, Wang X, Li B, Hu Z] Department of Intensive Care Unit, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, Shijiazhuang, China. [Rello J] Grup de Recerca Clínica/Innovació en la Pneumònia i Sèpsia (CRIPS), Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain. Barcelona, Spain & Clinical Research, CHU Nîmes, Nimes, France. [Kim WY] Department of Emergency Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea. [Wang X] Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China, Vall d'Hebron Barcelona Hospital Campus |
| Rok vydání: | 2021 |
| Předmět: |
Insuficiència renal aguda - Complicacions
Otros calificadores::Otros calificadores::/complicaciones [Otros calificadores] enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales::insuficiencia renal::lesión renal aguda [ENFERMEDADES] Original Article Septicèmia General Medicine Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Acute Kidney Injury [DISEASES] Other subheadings::Other subheadings::/complications [Other subheadings] |
| Zdroj: | Ann Transl Med Scientia |
| ISSN: | 2305-5839 |
| Popis: | Central venous pressure (CVP); Database; Mortality Pressió venosa central (PVC); Base de dades; Mortalitat Presión venosa central (PVC); Base de datos; Mortalidad Background: Sepsis has long been a life-threatening organ dysfunction. Sepsis associated acute kidney injury (SA-AKI) is an important complication of sepsis, as an important hemodynamic index, the impact of central venous pressure (CVP) on sepsis patients needs to be explored. Thus this study aimed to investigate the relationship between CVP and the mortality of SA-AKI. Methods: Clinical data of adult patients with sepsis-related acute kidney injury, defined as met both the Sepsis 3.0 criteria and the Kidney Disease Improving Global Outcomes Clinical Practice Guideline (KDIGO) criteria, were obtained from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. The included cohort was divided into a high CVP and a low CVP group were determined based on the cuf-off value from receiver operating characteristic curve, with propensity score-matched analysis of the 28-day mortality for both groups and sensitivity analysis using inverse the probability-weighting model, multifactorial regression, and doubly robust estimation, patients acquired chronic coronary syndrome (CCS) and diabetes were also taken into consideration. Results: Of 1,377 patients with sepsis-related acute kidney injury, low CVP group ( |
| Databáze: | OpenAIRE |
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