Investigation of 3D-printed chitosan-xanthan gum patches
| Autor: | Altan, Eray, Türker, Nurgül, Hindy, Osama Ali, Dirican, Zeynep, Bingöl Özakpınar, Özlem, Uzuner Demir, Ayşegül, Kalaskar, Deepak, Thakur, Sourbh, Gündüz, Oğuzhan |
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| Přispěvatelé: | ALTAN E., Turker N., Hindy O. A., Dirican Z., Ozakpinar Ö., Demir A. U., Kalaskar D., Thakur S., GÜNDÜZ O. |
| Rok vydání: | 2022 |
| Předmět: |
Cancer Research
Aging Polymers and Plastics Kimya (çeşitli) Clinical Biochemistry HYDROGELS Temel Bilimler (SCI) Genel Biyokimya Genetik ve Moleküler Biyoloji Physical Chemistry SCAFFOLDS Biochemistry Kimya Proses Kimyası ve Teknolojisi Polimerler ve Plastikler CHEMISTRY Structural Biology BİYOKİMYA VE MOLEKÜLER BİYOLOJİ Yaşlanma Biyokimya Drug Discovery İlaç Keşfi Moleküler Biyoloji Temel Bilimler Polysaccharides Bacterial Polimer Karakterizasyonu Fizikokimya Life Sciences 3D printing General Medicine Biyokimya Genetik ve Moleküler Biyoloji (çeşitli) MOLECULAR BIOLOGY & GENETICS POLİMER BİLİMİ Chemistry (miscellaneous) Wound dressing Printing Three-Dimensional Natural Sciences (SCI) Physical Sciences ACID Natural Sciences BIOCHEMISTRY & MOLECULAR BIOLOGY Sitogenetik Diğer Characterization of Polymers Life Sciences (LIFE) Molecular Biology and Genetics POLYMER SCIENCE FILMS Biochemistry Genetics and Molecular Biology (miscellaneous) General Biochemistry Genetics and Molecular Biology Biomaterials Yaşam Bilimleri CHEMISTRY APPLIED Optimisation Cytogenetic Molecular Biology Moleküler Biyoloji ve Genetik Chitosan Yapısal Biyoloji Process Chemistry and Technology General Chemistry IN-VITRO Bandages Genel Kimya KİMYA UYGULAMALI Klinik Biyokimya Fizik Bilimleri FTIR Yaşam Bilimleri (LIFE) Other Kanser Araştırmaları |
| Zdroj: | International Journal of Biological Macromolecules. 213:259-267 |
| ISSN: | 0141-8130 |
| Popis: | In this study, using a new polymer combination of Chitosan(CH)/Xanthan Gum(XG) has been exhibited for wound dressing implementation by the 3D-Printing method, which was fabricated due to its biocompatible, biodegradable, improved mechanical strength, low degradation rate, and hydrophilic nature to develop cell-mimicking, cell adhesion, proliferation, and differentiation. Different concentrations of XG were added to the CH solution as 0.25, 0.50, 0.75, 1, and 2 wt% respectively in the formic acid/distilled water (1.5:8.5) solution and rheologically characterized to evaluate their printability. The results demonstrated that high mechanical strength, hydrophilic properties, and slow degradation rate were observed with the presence and increment of XG concentration within the 3D-Printed patches. Moreover, in vitro cell culture research was conducted by seeding NIH 3T3 fibroblast cells on the patches, proving the cell proliferation rate, viability, and adhesion. Finally, 1% XG and 4% CH containing 3D-Printed patches were great potential for wound dressing applications. |
| Databáze: | OpenAIRE |
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