Significantly Improved Vascular Complications Among Women Undergoing Percutaneous Coronary Intervention

Autor: John F. Robb, Winthrop D Piper, Peter VerLee, Bina Ahmed, William J Phillips, Michael Herne, David J. Malenka, Thomas J. Ryan, Harold L. Dauerman
Rok vydání: 2009
Předmět:
Zdroj: Circulation: Cardiovascular Interventions. 2:423-429
ISSN: 1941-7632
1941-7640
DOI: 10.1161/circinterventions.109.860494
Popis: Background— Women are at a higher risk for bleeding/vascular complications (VC) related to cardiovascular procedures. Although the overall incidence of percutaneous coronary intervention (PCI)-related bleeding/VC has declined, the impact of this decline, specifically in women, is unknown. Methods and Results— We studied 13 653 female and 32 334 male consecutive cases, from 2002 to 2007, in the Northern New England PCI Registry. We sought to (1) compare absolute rates of bleeding/VC in women and men over time, (2) define predictors of bleeding/VC in women and men undergoing PCI, and (3) trend the impact of female gender in predicting bleeding/VC over time. Bleeding/VC was defined as any access-site vessel injury requiring surgical intervention or bleeding requiring transfusion. The overall risk of bleeding/VC was significantly higher in women versus men (4.5�1.3% versus 1.6�0.5%; P P Conclusion— Women undergoing PCI have had a significant decline in bleeding/VC rates during the last 6 years. Despite the improvement in procedural safety, female gender continues to be associated with a >2-fold risk of bleeding/VC compared with men.
Databáze: OpenAIRE