Pharmacological vs Exercise Stress Echocardiography for Detection of Cardiac Allograft Vasculopathy
| Autor: | Linda M. Cadaret, Angela J. Schadler, Alexandros Briasoulis, Noah N. Williford, Milena A. Gebska, Ily Kristine T. Yumul-Non, Carolyn Laxson, Richard E. Kerber, Robert M. Weiss, Paulino Alvarez |
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| Rok vydání: | 2019 |
| Předmět: |
Inotrope
medicine.medical_specialty Population Hemodynamics 030204 cardiovascular system & hematology Cardiac allograft vasculopathy 03 medical and health sciences 0302 clinical medicine Internal medicine Heart rate LVEF left ventricular ejection fraction medicine 030212 general & internal medicine education CAV cardiac allograft vasculopathy lcsh:R5-920 education.field_of_study Ejection fraction HR heart rate business.industry SBP systolic blood pressure MPHR maximum predicted HR Blood pressure Cardiology Dobutamine Original Article lcsh:Medicine (General) business medicine.drug |
| Zdroj: | Mayo Clinic Proceedings: Innovations, Quality & Outcomes Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 4, Iss 1, Pp 65-75 (2020) |
| ISSN: | 2542-4548 |
| Popis: | Objective: To test the hypothesis that exercise and dobutamine would provide levels of cardiac stress that are comparable to those achieved in a general stress test population, and to one another, in heart transplant recipients. Patients and Methods: From February 10, 2015, to December 31, 2017, 81 patients underwent exercise stress (N=45) or dobutamine stress (N=36) echocardiography at a mean ± SD of 11±14 years (range, 1-29 years) after heart transplant. Hemodynamic and inotropic responses were compared between groups, and to a prior test, longitudinally. The primary outcome was peak heart rate (HR) × systolic blood pressure (SBP). Results: Peak exercise HR × SBP × 10−3 was a mean ± SD of 24.9±4.9 mm Hg/min for exercise stress vs 21.2±3.4 mm Hg/min during dobutamine stress (P |
| Databáze: | OpenAIRE |
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