Additional file 1 of Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy

Autor: Liu, Shuya, Zhao, Yu, Lu, Shun, Zhang, Tianran, Lindenmeyer, Maja T., Nair, Viji, Gies, Sydney E., Wu, Guochao, Nelson, Robert G., Czogalla, Jan, Aypek, Hande, Zielinski, Stephanie, Liao, Zhouning, Schaper, Melanie, Fermin, Damian, Cohen, Clemens D., Delic, Denis, Krebs, Christian F., Grahammer, Florian, Wiech, Thorsten, Kretzler, Matthias, Meyer-Schwesinger, Catherine, Bonn, Stefan, Huber, Tobias B.
Rok vydání: 2023
DOI: 10.6084/m9.figshare.22616278.v1
Popis: Additional file 1: Figure S1. Characterization of BTBR ob/ob podocyte-reporter mice. Figure S2. Overview of the single cells from DN and control kidney samples. Figure S3. Distributions of cells across conditions and individual kidney samples. Figure S4. FACS analysis of podocytes (podo), glomerular endothelial cells (gECs) and mesangial cells (mesan) from the isolated mouse glomeruli. Figure 5S. Bulk RNA-seq results for FACS-sorted glomerular cells. Figure S6. Transcriptional regulations in DN mice. Figure S7. snRNA-seq of early human diabetic nephropathy and ex-vivo-perfused pig kidney tissue. Supplementary methods: FACS-sorted glomerular cells. Urine and serum analysis. Histological and ultrastructural analysis.
Databáze: OpenAIRE