Forelimb skeletal scintigraphy responses in previously untrained Thoroughbreds undergoing initial treadmill training
| Autor: | O. J. Inoue, Jonathan H. Foreman, A. R. Twardock, M. D. Chambers, S. K. Kneller |
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| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty Lameness Animal Scintigraphy Bone and Bones Carpus Animal Statistical significance Physical Conditioning Animal Forelimb medicine Animals Horses Prospective Studies Treadmill Prospective cohort study Muscle Skeletal Radionuclide Imaging medicine.diagnostic_test business.industry Horse General Medicine Surgery medicine.anatomical_structure Lameness Anesthesia Third metacarpal bone Exercise Test Female Horse Diseases Joints business |
| Zdroj: | Equine veterinary journal. Supplement. (34) |
| Popis: | Scintigraphy has been used in numerous clinical settings to examine horses to determine the origin of lameness problems, but it has not been used previously to monitor prospectively the skeletal responses of a group of similarly-trained racehorses. Our hypothesis was that in naïve Thoroughbred (TB) racehorses, initial treadmill training induces increased radiopharmaceutical uptake in high-motion joints and in the dorsal third metacarpal bone (MC3). Eight previously-untrained TB racehorses underwent sequential skeletal scintigraphic examinations as they exercised daily for 9 weeks on an inclined treadmill. At the end of Weeks 0 (pre-training), 3 (trotting at 4.2 m/s and initial galloping), 6 (galloping at 7.5 m/s), and 9 (sprinting 600 m at 12.5 m/s), horses received 140 mCi 99m Technetium-methylene diphosphonate i.v. followed by a standard skeletal scintigraphic forelimb examination 2 h later. Views were graded for increased radiopharmaceutical uptake by 3 co-investigators who were blinded to horse identification, breed, sex, date, and clinical findings. Results were compared before and after training for each skeletal location using the Mann-Whitney Rank Sum Test with the level of significance set at P0.05. Initial treadmill training resulted in increased radiopharmaceutical uptake in the carpus (P = 0.031), metacarpophalangeal joint (P = 0.021), proximal phalanx (P = 0.035), and distal phalanx (P = 0.003). Training did not affect dorsal MC3 radiopharmaceutical uptake (P0.05). |
| Databáze: | OpenAIRE |
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