Synthesis of Esters Containing Cinnamoyl Motif with Potential Larvicide Action: A Computational, Ecotoxicity and in Vitro Cytotoxicity Assessments

Autor:	Paulo Ricardo dos Santos Correia, Cenira Monteiro de Carvalho, Cristhyan Rychard da Silva Cunha, Rafael Antonio Santos da Silva, Monaly de Oliveira Lima, Saraliny Bezerra França, Emiliano de Oliveira Barreto, Josealdo Tonholo, Dimas José da Paz Lima
Rok vydání:	2022
Předmět:	Insecticides Plant Extracts Bioengineering Esters General Chemistry General Medicine Biochemistry Molecular Docking Simulation Aedes Larva Acetylcholinesterase Molecular Medicine Animals Molecular Biology
Zdroj:	Chemistrybiodiversity. 19(11)
ISSN:	1612-1880
Popis:	An increasing morbidity and mortality rate has been related to arboviruses transmitted by Aedes aegypti. Compounds with cinnamoyl moiety represent an alternative against mosquitos, considering their larvicidal activity. This study aimed to assess the larvicidal activity of cinnamic ester derivates against Aedes aegypti larvae, along with evaluating their toxicity effect to assess its safety as a larvicide. Ethyl cinnamate demonstrated larvicidal activity (LC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f38ba1575eda48a5c5f74f3d1a8fb63 https://pubmed.ncbi.nlm.nih.gov/36174042 Zobrazit plný text záznamu Plný text