FREQUENCY AND OUTCOME OF PATIENTS WITH ACUTE RENAL FAILURE HAVE MORE CAUSES THAN ONE IN ETIOLOGY

Autor:	N. Yilmaz Selçuk, Nedim Yilmaz Selçuk, Ali Riza Odabas, Ramazan Çetinkaya, Halil Zeki Tonbul, Ayla San
Rok vydání:	2000
Předmět:	Adult Male medicine.medical_specialty Kidney Function Tests Critical Care and Intensive Care Medicine Gastroenterology Renal Dialysis Risk Factors Oliguria Internal medicine Epidemiology medicine Humans Prospective Studies Aged Chi-Square Distribution business.industry Septic shock Incidence Incidence (epidemiology) General Medicine Acute Kidney Injury Middle Aged Prognosis medicine.disease Survival Analysis Surgery Diarrhea Nephrology Etiology Female Anuria medicine.symptom business Kidney disease
Zdroj:	Renal Failure. 22:459-464
ISSN:	1525-6049 0886-022X
DOI:	10.1081/jdi-100100887
Popis:	In literature, there was little data about frequency and outcome of ARF with two or more causes in etiology. Therefore, the aim of this study was to search this issue. This series included 339 patients with ARF from Jan 1,1987 to Jan 1,1999. Fourty-six (30 males) of all patients (13.5%) had two or more causes in etiology of ARF. Of these patients, causes were prerenal and renal in 26 (56%), prerenal, renal and postrenal in 12 (26%), renal and postrenal in 4 (9%), and prerenal and postrenal in 4 (9%). The most frequent cause is diarrhea and vomiting in prerenal, gentamycin usage in renal and prostate hypertrophy in postrenal. Of these patients, there was oliguria in 32 (70%), anuria in 8 (17%) and non-oliguria in 6 (13%). Treatment modalities of patients was only medical in 19 (41%), dialysis in addition to medical therapy in 27 (59%). In spite of treatment, 5 (10.8) of patients with two or more causes in etiology died. Causes of death were uremic coma in 2, cardiac disorders in 2 and septic shock in 1. Three (11.2%) of other patients with one cause died. Mortality rates were not different (chi2: 0.0298, p0.5). Cortical necrosis was diagnosed in one patient with multiple etiology and 2 of other patients. Finally, frequency of ARF with two or more etiologic causes was 13.5%, and most frequent causes were hypovolemia and nephrotoxic drugs. Outcome of these patients was similar to other patients with one cause.
Databáze:	OpenAIRE
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