The health-related quality of life and psychological profile in patients with oropharyngeal Pemphigus Vulgaris in complete clinical remission: A case-control study

Autor: Stefania Leuci, Daniela Adamo, Noemi Coppola, Elena Calabria, Giuseppe Pecoraro, Massimo Aria, Michele D. Mignogna
Přispěvatelé: Calabria, E., Adamo, D., Leuci, S., Pecoraro, G., Coppola, N., Aria, M., Mignogna, M. D.
Rok vydání: 2020
Předmět:
Zdroj: Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyREFERENCES. 50(5)
ISSN: 1600-0714
Popis: Background: Pemphigus Vulgaris (PV) is a severe autoimmune blistering disease which may affect the patient's health-related quality of life (HR-QoL) and mood even during quiescent disease activity. We sought to evaluate HR-QoL, quality of sleep (QoS), anxiety and depression in oropharyngeal PV patients (OPV) in complete clinical remission on or off therapy (CCR-on, CCR-off). Methods: Thirty OPV patients and 30 healthy controls were enrolled. The Short Form 36 Health Survey Questionnaire (SF-36), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Hamilton Rating Scale for Depression (HAM-D) and Hamilton Rating Scale for Anxiety (HAM-A) were administered. Descriptive statistics, including the Mann-Whitney U test and hierarchical multiple linear regression analysis, were used. Results: The OPV patients had statistically lower scores in the majority of items of the SF-36 and higher scores in the PSQI, HAM-A and HAM-D than the healthy controls (P 5) with higher scores in the SF-36, HAM-A and HAM-D compared with the good sleepers (PSQI
Databáze: OpenAIRE