A Case of Synchronous Malignant and Benign Granular Cell Tumor of the Vulva
| Autor: | Joanna C. Walsh, Katherina Baranova, Jacob McGee, Emily A. Goebel |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty Soft Tissue Neoplasm Benign Granular Cell Tumor medicine.medical_treatment Biopsy Physical examination Soft Tissue Neoplasms Malignancy Pathology and Forensic Medicine Vulva Lesion Neoplasms medicine Humans medicine.diagnostic_test Vulvar Neoplasms business.industry Vulvectomy Obstetrics and Gynecology Middle Aged medicine.disease medicine.anatomical_structure Granular Cell Tumor Female medicine.symptom business |
| Zdroj: | International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 40(5) |
| ISSN: | 1538-7151 |
| Popis: | Granular cell tumors (GCT) are rare soft tissue neoplasms, which seldom occur in the vulva. They are more commonly benign, but malignant GCT do occur. We report a case of a 50-yr-old postmenopausal woman who presented with a vulvar lesion that was diagnosed as GCT on biopsy. Imaging and clinical examination revealed an enlarged, likely positive lymph node. Pathology of the subsequently resected total deep vulvectomy specimen showed 2 histologically distinct GCTs. The larger lesion met criteria for malignancy and histologically corresponded to metastatic deposits seen in the pelvic lymph nodes. The separate smaller lesion was histologically benign. This case illustrates a malignant GCT with a synchronous, likely benign GCT both occurring in the vulva. Our case demonstrates the application of histologic criteria in the diagnosis of malignant and benign GCT with discussion on the diagnosis and treatment of this rare tumor. |
| Databáze: | OpenAIRE |
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