Atrophy of the basal ganglia as the initial diagnostic sign of germinoma in the basal ganglia
| Autor: | Kunio Sakai, S. Tokiguchi, K. Ishikawa, M Yamada, Naoya Takahashi, J. Ito, Kouichirou Okamoto, T. Furusawa, Ken Morii |
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| Rok vydání: | 2002 |
| Předmět: |
Male
Pathology medicine.medical_specialty Adolescent Central nervous system Thalamus Basal Ganglia Central nervous system disease Atrophy Basal ganglia Humans Medicine Radiology Nuclear Medicine and imaging Retrospective Studies Germinoma medicine.diagnostic_test Brain Neoplasms business.industry Magnetic resonance imaging Anatomy medicine.disease Magnetic Resonance Imaging Hyperintensity Radiography medicine.anatomical_structure Neurology (clinical) Cardiology and Cardiovascular Medicine business |
| Zdroj: | Neuroradiology. 44:389-394 |
| ISSN: | 1432-1920 0028-3940 |
| Popis: | Germ-cell tumors of the central nervous system generally develop in the midline, but the tumors can also occur in the basal ganglia and/or thalamus. However, MR images have rarely been documented in the early stage of the tumor in these regions. We retrospectively reviewed MR images obtained on admission and approximately 3 years earlier in two patients with germinoma in the basal ganglia, and compared them with CT. In addition to hyperdensity on CT, both hyperintensity on T1-weighted images and a small hyperintense lesion on T2-weighted images were commonly seen in the basal ganglia. These findings may be early MRI signs of germinoma in this region, and the earliest and most characteristic diagnostic feature on MRI was atrophy of the basal ganglia, which was recognizable before development of hemiparesis. |
| Databáze: | OpenAIRE |
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