Function and regulation of Rnd proteins
| Autor: | Pierre Chardin |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
rho GTP-Binding Proteins
biology Rnd3 Cell Cycle Arp2/3 complex macromolecular substances Cell Biology Cell cycle Actin cytoskeleton Actins Axons Cell biology Contractility Transformation (genetics) Smooth muscle Neurites biology.protein Animals Humans Molecular Biology Cytoskeleton Function (biology) |
| Zdroj: | Nature Reviews Molecular Cell Biology. 7:54-62 |
| ISSN: | 1471-0080 1471-0072 |
| DOI: | 10.1038/nrm1788 |
| Popis: | The Rnd proteins, which form a distinct sub-group of the Rho family of small GTP-binding proteins, have been shown to regulate the organization of the actin cytoskeleton in several tissues. In the brain, they participate in neurite extension, whereas in smooth muscle, they modulate contractility. Recent evidence has shown that Rnd3 (RhoE) is also involved in the regulation of cell-cycle progression and transformation, indicating that these proteins might have other, as yet unexplored roles. |
| Databáze: | OpenAIRE |
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