Relative Risk of Mortality Associated With Diabetes as a Function of Birth Weight
| Autor: | Kent R. Bailey, Joseph L. Melton, Cynthia L. Leibson, Pasquale Palumbo, James P. Burke, Jessica Forsgren, Jeanine E. Ransom |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Risk Pediatrics medicine.medical_specialty Endocrinology Diabetes and Metabolism Birth weight Population Diabetes mellitus Internal Medicine medicine Birth Weight Humans Risk factor education Aged Aged 80 and over Advanced and Specialized Nursing Sex Characteristics education.field_of_study Proportional hazards model business.industry Hazard ratio Middle Aged medicine.disease Vital Statistics Low birth weight Diabetes Mellitus Type 2 Relative risk Female medicine.symptom business |
| Zdroj: | Diabetes Care. 28:2839-2843 |
| ISSN: | 1935-5548 0149-5992 |
| Popis: | OBJECTIVE—Birth weight is a risk factor for both diabetes and mortality. Diabetes is a risk factor for mortality. Whether the excess mortality observed for diabetes varies with birth weight is unclear. RESEARCH DESIGN AND METHODS—Among all 2,508 Rochester, Minnesota, residents who first met research criteria for adult-onset diabetes in 1960–1995, 171 were born locally in-hospital after 1922 (i.e., birth weights available) as singleton, term infants. Each case subject and two age- and sex-matched nondiabetic control subjects (born locally, residing locally when the case subject met the criteria for diabetes) were followed through 31 December 2000 for vital status. RESULTS—Of the diabetic case subjects, 16% (27 of 171) died vs. 7% (25 of 342) of control subjects (P = 0.004). The difference was less for normal-birth-weight (NBW) (2,948– CONCLUSIONS—The excess mortality observed for diabetes appears disproportionately concentrated among abnormal-birth-weight individuals, thus identifying a subset of at-risk diabetic individuals and reinforcing the importance of NBW deliveries. |
| Databáze: | OpenAIRE |
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