Associations between presence of diabetes, mortality and fracture type in individuals with a hip fracture

Autor: Bart Spaetgens, Steffie H.A. Brouns, Aimée E.M.J.H. Linkens, Martijn Poeze, René H.M. ten Broeke, Renée A.G. Brüggemann, Walther Sipers, Ronald M.A. Henry, Nordin M.J. Hanssen
Přispěvatelé: RS: Carim - B04 Clinical thrombosis and Haemostasis, Interne Geneeskunde, MUMC+: MA Alg Interne Geneeskunde (9), RS: NUTRIM - R3 - Respiratory & Age-related Health, MUMC+: MA Heelkunde (9), MUMC+: NAZL en ROAZ (9), Surgery, MUMC+: MA Orthopedie (3), Orthopedie, MUMC+: MA Orthopedie (9), MUMC+: CAKZ Medische afdeling SEH (5), MUMC+: HVC Pieken Maastricht Studie (9), RS: Carim - V01 Vascular complications of diabetes and metabolic syndrome, Vascular Medicine, ACS - Atherosclerosis & ischemic syndromes, ACS - Diabetes & metabolism, Amsterdam Gastroenterology Endocrinology Metabolism
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Diabetes Research and Clinical Practice, 192:110084. Elsevier Ireland Ltd
Diabetes research and clinical practice, 192:110084. Elsevier Ireland Ltd
ISSN: 1872-8227
0168-8227
Popis: AIMS: An overlooked aspect of diabetes is an increased risk of hip fractures, with associated mortality. We investigated whether fracture type and/or burden of comorbidities explains the increased risk of mortality in diabetes after hip fracture.METHODS: For this cohort study, we used a de-identified data set of hip fracture patients registered in a quality-of-care registry (2017/2018) included in Maastricht University Medical Centre.RESULTS: Among 594 hip fracture patients, 90 (15.2 %) had diabetes. Median (IQR) age was 82 (71-87) years and 63.8 % were women. Compared to patients without, patients with diabetes had higher median Charlson Comorbidity Index [1 (0-2) vs 0 (0-2), P < 0.001)] and were more likely to sustain intertrochanteric/subtrochanteric fractures [54.4 vs 38.7 %, P = 0.02]. Over a median follow-up of 2.7 (1.6-3.3) years, crude mortality rate was 30.8 % in patients without and 50.0 % in patients with diabetes. This association remained unaltered after adjustment for age, sex, BMI, fracture type or burden of co-morbidities.CONCLUSION: Individuals with diabetes display a greatly increased absolute mortality risk after hip fracture. This association was not attenuated after adjustment for fracture type or non-diabetes associated co-morbidity. These findings have important implications for diabetes care in hip fracture patients, and underline the importance of fracture prevention.
Databáze: OpenAIRE
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