Treatment Differences in Chronic Heart Failure Patients With Reduced Ejection Fraction According to Blood Pressure
| Autor: | Jesse F. Veenis, Hans-Peter Brunner-La Rocca, Marco W.F. van Gent, Gerard C.M. Linssen, Arno W. Hoes, Jasper J. Brugts |
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| Přispěvatelé: | Cardiology, Cardiologie, MUMC+: MA Med Staf Spec Cardiologie (9), RS: Carim - H02 Cardiomyopathy |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
safety medicine.medical_specialty Time Factors diagnosis esc guidelines efficacy heart failure Ventricular Function Left left Internal medicine medicine Humans In patient Registries Aged Netherlands Aged 80 and over therapy OUTCOMES Ejection fraction Ventricular function business.industry MORTALITY association blood pressure Cardiovascular Agents Stroke Volume Guideline Middle Aged medicine.disease outpatients Cross-Sectional Studies Treatment Outcome Blood pressure Heart failure Cardiology ventricular function Drug Therapy Combination Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Circulation-Heart Failure, 13(5). Lippincott Williams & Wilkins Circulation-Heart Failure, 13(5):006667. LIPPINCOTT WILLIAMS & WILKINS |
| ISSN: | 1941-3289 |
| Popis: | Background: Prescribed dosages of heart failure (HF) therapy in patients with a reduced left ventricular ejection fraction remain lower than guideline recommended. It remains unclear whether systolic blood pressure (BP) influences prescription of HF drugs to HF patients with a reduced left ventricular ejection fraction in a European setting. This study aimed to investigate the role of systolic BP on the prescription rate and actual dose of guideline-recommended HF therapy. Methods: A total of 8246 patients with chronic HF with a reduced left ventricular ejection fraction from 34 Dutch outpatient HF clinics were included. Detailed information on prescription rates and dosages of HF drugs were assessed according to systolic BP categories ( Results: Patients with systolic BP P P for all trends, P for all trends, Conclusions: In this large cross-sectional cohort of patients with reduced left ventricular ejection fraction, patients with lower systolic BP receive more HF drugs but at lower dose relative to the target dose recommended in HF guidelines. Discussion is warranted regarding what target BP is acceptable and what should be limiting factors in uptitration to adequate levels of HF medication. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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