Comparison of virtual reality rehabilitation and conventionalrehabilitation in Parkinson’s disease: a randomised controlledtrial

Autor: Costanza Pazzaglia, Diego Ricciardi, Carlo Minganti, R. Lo Monaco, Isabella Imbimbo, Eliana Tranchita, Luca Padua, Attilio Parisi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
030506 rehabilitation
medicine.medical_specialty
Settore M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICA
medicine.medical_treatment
Physical Therapy
Sports Therapy and Rehabilitation

Virtual reality
law.invention
03 medical and health sciences
Disability Evaluation
0302 clinical medicine
Randomized controlled trial
Quality of life
law
Dash
Medicine
Humans
Single-Blind Method
Conventional therapy
030212 general & internal medicine
Prospective Studies
Prospective cohort study
Gait
Postural Balance
Physical Therapy Modalities
Aged
Rehabilitation
business.industry
Parkinson Disease
Rehabilitation in Parkinson's disease
Middle Aged
Functional outcome
Confidence interval
Settore MED/26 - NEUROLOGIA
Physical therapy
Quality of Life
Parkinson’s disease
Female
0305 other medical science
business
Settore MED/34 - MEDICINA FISICA E RIABILITATIVA
Popis: Objective To compare a 6-week virtual reality (VR) rehabilitation programme with a conventional rehabilitation programme in patients with Parkinson’s disease. Design Prospective, single-blinded, randomised controlled trial. Setting Outpatients. Participants Fifty-one patients with Parkinson’s disease were assigned at random to a VR rehabilitation programme or a conventional rehabilitation programme. Interventions Both programmes ran for 6 consecutive weeks, with a 40-minute session three times per week. Main outcome measures The Balance Berg Scale (BBS) was used to measure balance. Secondary outcome measures were: Dynamic Gait Index (DGI) to evaluate ability to adapt gait to complex walking tasks; Disabilities of the Arm, Shoulder and Hand (DASH) scale to measure performance of the upper limb; and Short Form 36 (SF-36) to evaluate quality of life. Results The VR rehabilitation programme led to an increase in BBS score {45.6 [standard deviation (SD) 7.9] vs 49.2 (SD 8.1), mean difference 3.6, 95% confidence interval (CI) 1.3 to 5.9; P = 0.003}, DGI score [18.7 (SD 4.7) vs 20.2 (SD 4.2), mean difference 1.6, 95% CI 0.6 to 2.5; P = 0.003] and SF-36 mental composite score [37.7 (SD 11.4) vs 43.5 (SD 9.2), mean difference 5.8, 95% CI 0.4 to 11.3; P = 0.037], and a decrease in DASH scale score [29.6 (SD 17.5) vs 21.6 (SD 15.1), mean difference −7.9, 95% CI −13.7 to −2.2; P = 0.009]. In contrast, the conventional rehabilitation programme only led to a decrease in DASH scale score [30.3 (SD 18.1) vs 25.1 (SD 15.8), mean difference −5.2, 95% CI −8.8 to −1.5; P = 0.007]. Conclusion These findings suggest that rehabilitation is useful in Parkinson’s disease, and the VR rehabilitation programme was more effective in determining overall improvement than the conventional rehabilitation programme. Clinical trial registration number : NCT02807740.
Databáze: OpenAIRE